For it to be the Body and Blood of Jesus Christ, yes. Jesus instituted His church, to, among other things, have Bishops and Priests capable of consecrating the bread and wine, which then becomes His Body and Blood.
Protestant ministers are not Priests–or even Catholic–and as such cannot do this. Even if they COULD, though, they wouldn’t because they don’t BELIEVE that the bread and wine can possibly change into the Body and Blood. If they did, they would be Catholic! lol